Investigations on the Efficacy of Some Anticestode Compounds against Echinococcus granulosus in the Dog *

نویسنده

  • Ferenc HOLLÓ
چکیده

ABSTRACT. The efficiency of single treatments w i th bunamidine hydroxynaphthoate (BHN, Burroughs Wellcome and Co. ), bunamidine hydrochlor ide (BHC1, "Scolaban" Burroughs Wellcome and Co. ), niclosamide (NA, "Dayermin" Chinoin) and cantrodifene (CF, "Lopatol" , CIBA-GEIGY) against 6-week old E . ganulosus was tested on 113 exper imental ly infected dogs'. BHN at 100 mg /kg removed 95.1-97.2 per cent of the worms f rom 89 per cent of the treated dogs. FoUowing treatment with NA or CF, considerable w o r m reduction was recorded in 28 and 14 per cent of the animals, respectively, while results of the BHClt rea tment were inconclu­ sive. BHN i n biscui t formulat ion was found to f u l f i l l p rac t ica l requirements of control schemes involving regular dosing.

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تاریخ انتشار 2011